Hand Sanitizer Ekstrak Etanol Daun Simpur (Dillenia suffruticosa) sebagai Antiseptik Bakteri Escherechia coli dan Staphilococcus aureus

نویسندگان

چکیده

Penyakit infeksi menempati urutan ketiga dari sepuluh penyakit penyebab kematian tertinggi di Indonesia. Cuci tangan menggunakan hand sanitizer merupakan teknik dasar yang paling penting dalam pencegahan dan pengontrolan penularan infeksi. Penelitian tentang Hand ekstrak etanol daun simpur (Dillenia suffruticosa) sebagai antiseptik terhadap bakteri Eschericia coli Staphylococcus aureus telah dilakukan. Tujuan penelitian ini adalah untuk menentukan senyawa fitokimia, aktivitas, stabilitas sediaan gel simpur. Hasil skrining fitokimia menunjukkan bahwa positif mengandung flavonoid, alkaloid, terpenoid, fenol, saponin. Pengujian antibakteri metode difusi kertas cakram media Muller Hinon Agar (MHA) dengan 3 replikasi hasil baik pada tiga konsentrasi yaitu F1 (5%); F2 (7,5%); F3 (10%). Zona hambat terbesar terdapat (10%) menghasilkan rata-rata zona sebesar 9,87 mm E. 7,15 S. aureus. Ekstrak bahan aktif terbukti efektif menghambat atau membunuh bakteri. mengindikasikan berpotensi digunakan antiseptik.

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ژورنال

عنوان ژورنال: Jurnal Sains dan Kesehatan

سال: 2023

ISSN: ['2303-0267', '2407-6082']

DOI: https://doi.org/10.25026/jsk.v5i3.1655